Prebiotics: The Microbiome Frontier
to Enhance Health and Wellbeing
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THE FIRST HUMAN PREBIOTIC: HUMAN MILK OLIGOSACCHARIDES
The third most abundant component in human milk are prebiotic substances that serve as food for the infant’s gut microbiota. It is astounding to consider that highly nutritious human milk, designed through thousands of years of evolution to nourish a newborn infant, contains large quantities of a substance that, for…
DOES A DIVERSE ARRAY OF BACTERIA IN THE GUT MICROBIOTA CONTRIBUTE TO PROTECTION AGAINST PATHOGEN INFECTION?
The presence of a diverse array of bacteria in the gut microbiome contributes to protection against pathogen infection. Among the mechanisms of protection, the presence of gut bacteria with diverse metabolic requirements makes it difficult for pathogens to find sufficient food thereby reducing the incidence of disease. Protection from infection…
DOES A PREGNANT WOMAN’S GUT MICROBIOTA COMMUNICATE WITH HER DEVELOPING FETUS?
Yes, as biomolecules produced by bacteria in the woman’s gut are encapsulated in extracellular vesicles (EVs) that accumulate in the amniotic fluid surrounding the fetus. The EVs are ingested by the fetus. Specifically, bacteria in the mother’s large intestine or colon produce EVs. These EVs carry biomolecules, such as protein…
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